3 Natural Compounds work together to Enhance the Entourage Effects of Each
Cannabidiol
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Palmitoylethanolamide
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Cholecalciferol
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Cannabidiol
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Palmitoylethanolamide
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Cholecalciferol
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What is Full Spectrum CBD?“Cannabis is inherently polypharmaceutical,” Dr. John McPartland notes, “and synergy arises from interactions between its multiple components.” Full Spectrum CBD oil, unlike CBD isolate products, includes a wide range of cannabinoids present in the cannabis or hemp plant. There are over 100 ‘identified’ compounds in the cannabis plant. Full spectrum CBD also contains a variety of essential vitamins, minerals, fatty acids, protein, chlorophyll, terpenes, flavonoids, and fiber.
While most of these compounds have their own therapeutic benefit, they combine synergistically to magnify and provide far better performance than any single compound alone, and that includes CBD. This interactive synergy between cannabis compounds has been coined the “entourage effect.” The different compounds can amplify each other’s chemistry, making the overall plant more effective. |
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Vitamin D3 is actually an Endocrine System produced Steroid Hormone. It was unfortunately mislabeled when originally discovered. The word “vitamin” generally applies to substances that our body can’t make, but need, so we must get vitamins from exogenous sources. Vitamin D3 is instead, an endogenous hormone that we make naturally in our skin from exposure to the sun's UVB rays. It is the most ancient hormone, and important to the function and balance of other hormones such as estrogen or testosterone. It is called "The Sunshine Vitamin", but more accurately would be called "The Sunshine Hormone".
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The term “entourage effect” describes the synergistic manner in which natural compounds work together to produce therapeutic benefits. When we combine certain compounds in their natural state, we don’t end up with the sum of each part; instead, we get a multiplying effect. The different compounds can amplify each other’s chemistry, making the combined product more effective in addressing health issues.
As it relates specifically to the ECS, PEA and Vitamin D3 have been shown to produce an “entourage effect, increasing receptors affinity to enhance endogenous anandamide activity and/or reducing enzymatic anandamide degradation” |