What Exactly Is CBD?

CBD is short for cannabidiol, a natural ingredient derived from the hemp plant. In addition to being entirely natural and safe, CBD is extremely versatile. After it is extracted from hemp, CBD can be manufactured into a full spectrum of products such as oils, edibles, beverages, sprays and topical creams and balms. Although these formulas have different tastes, shapes, and delivery methods, they all produce similar effects. CBD is not known to produce any significant side-effects, and it contains no addictive properties.

How Does CBD Relieve Pain?

The body contains cannabinoid receptors throughout the spinal cord, central nervous system and tissues. After researchers began discovering these receptors in 1988, they began to look into their influence on a variety of medical conditions, including chronic pain.

The two main receptors, CB1 and CB2, work somewhat differently. CB1 is more prevalent and influences the stimulation of nerve cells. CB2 is involved in mediating pain and suppressing inflammation. Proteins that bind to these receptors are called endocannabinoids. These work with the endocannabinoid system to provide relaxation, regulate appetite, help people sleep, control memory functions and influence learning. CBD is an exogenous cannabinoid. It comes from outside of the body but mimics some of the actions of endocannabinoids, indirectly working on various receptors to control pain.

Introducing exogenous cannabinoids to the system with CBD oil may enhance the body’s own pain-relieving processes. CBD doesn’t bind to CB1 and CB2 receptors. However, it does alter the way that certain neurotransmitters communicate with those receptors, exerting its effects indirectly. CB2 receptors are found in immune tissues throughout the body and are increased in the brain in disease or following injury. Their activation reduces inflammation which lessens pain and reduces the damaging consequences that chronic inflammation has on brain function and risk for developing brain diseases.

CBD and Inflammation

The cannabis plant creates important pain-relieving molecules called "flavonoids" that are 30 times more powerful at reducing inflammation than aspirin. Cannflavins would target pain with a different approach, by reducing inflammation.

Using a combination of biochemistry and genomics, researchers determined how cannabis makes two important molecules called cannflavin A and cannflavin B. Known as “flavonoids,” cannflavins A and B were first identified in 1985, when research verified they provide anti-inflammatory benefits that were nearly 30 times more effective gram-for-gram than acetylsalicylic acid (sold as Aspirin). These molecules are non-psychoactive and they target the inflammation at the source, making them ideal painkillers.

What Types of Pain Can CBD Treat?

CBD has been studied for its ability to relieve various types of pain, including:
• Chronic pain
• Arthritis
• Pain and Discomfort associated with osteoporosis 
• Nerve pain
• Spasm-related pain
• Sports pain
• Migraine
• Digestive pain
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Why Topical CBD is ideal for pain?

Topical CBD is ideal for local application to an affected area of skin, muscle, or joints. CBD applied topically tends to stay concentrated in the area where it was applied, unlike edible and sublingual CBD, which spreads throughout the entire body via the bloodstream. The CBD is absorbed into the skin and since it does not have to be digested like oils or edibles, the products work quickly and effectively, focusing right on the area where it is needed.  CBD has many benefits when used topically and without the potential side-effects of smoking, vaping or edibles;
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For many people living with chronic pain, topical CBD products provide the best relief. Topicals go directly to the source of pain, and can provide relief from sore muscles, joints, tendons, and more for seniors, athletes, workers, and anyone else suffering from aches and pains – long-term, short-term, acute and chronic.

Topical application of cannabis products and CBD oil can also bring therapeutic results because of the cannabinoid receptors on the skin. Moreover, applying CBD in gel, oil or lotion form is the most effective way to spot-treat localized inflammation and pain. This type of treatment can be effective on more lasting issues such as arthritis and chronic pain.
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More Info on CBD

The positive effects of CBD continue to be studied by scientists. They have already discovered the connection of CBD boosting the function of the cannabinoid receptors to produce soothing, relaxing effects without producing a "high." In some countries, CBD is already classified as a medication due to its proven effectiveness, but it is still currently available in the United States without a prescription.  Many people choose CBD to help manage their pain, while others supplement daily with healthy CBD to maintain and promote their general well-being, mood and stress levels.  CBD is non habit-forming, and can be taken daily.   It has no known psychoactive properties, and is believed to not impair users in any way.

CBD for pain means lowering your reliance on over-the-counter medicines like ibuprofen and acetaminophen, which can cause stomach and organ issues over long periods of time, and on prescription painkillers that can cause addiction and dependence.  

RESEARCH ARTICLES, WITH SELECT QUOTES
Click on buttons for quote source and Full Research documents and articles.


CBD could help to treat arthritis and relieve the associated inflammatory pain:
  • A 2011 study found that CBD helped to reduce inflammatory pain in rats by affecting the way that pain receptors respond to stimuli.
  • A 2014 review of the existing body of research on animals concluded that CBD may be an effective treatment for OA.
  • A 2016 study found that the topical application of CBD had the potential to relieve pain and inflammation associated with arthritis.
  • A 2017 study found that CBD might be a safe and useful treatment for OA joint pain.

Pain ReliefPain relief is amongst the top benefits of using CBD oil. It is amongst the main reasons people are paying attention to this oil. Evidence suggests that high-quality CBD oil can inhibit the neural transmission of pain. As a result, the person can relax without the need to consume large amounts of pain medication.
Conclusion: These studies demonstrate transdermal administration of CBD has long-lasting therapeutic effects without psychoactive side-effects. Thus, use of topical CBD has potential as effective treatment of arthritic symptomatology. At present, one in five (21%) adults worldwide are diagnosed with some form of arthritis by their physicians (Helmick et al., 2008). The data presented suggest transdermal CBD is a good candidate for developing improved therapies for these debilitating disease.
The data presented here indicate that local administration of CBD blocked OA pain. Prophylactic CBD treatment prevented the later development of pain and nerve damage in these OA joints. These findings suggest that CBD may be a safe, useful therapeutic for treating OA joint neuropathic pain.

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