What Is CBD? CBD is an abbreviation for Cannabidiol, a chemical compound found naturally in the cannabis plant. Over the past 40 years, there have been numerous studies that highlight the potential benefits of CBD and how it can support the Endocannabinoid System (ECS), the network of receptors in every person
WILL CBD MAKE ME “HIGH”?
No. You will not experience a "high" feeling from ingesting or topically applying CBD oil products. CBD oil is made from the hemp plant which is high in CBD and low in THC, unlike medical marijuana products that come from the female cannabis plant. Containing only trace amounts of THC, the extracted CBD oil will not cause the psychoactive effects similar to those of tetrahydrocannabinol (THC), present in marijuana. Cannabidiol is just one of over 85 cannabinoids presently identified in the cannabis plant and is the second most abundant cannabinoid in marijuana after THC. CBD is naturally occurring in the human body (through our Endocannabinoid Systems), so it interacts with our naturally occurring systems, but is non-psychotropic. This makes it a safer, less controversial alternative, while still offering significant health benefits.
HOW DOES CBD WORK IN THE BODY? CBD or cannabidiol is the main active compound in hemp and unlike THC, it is not psychoactive, so it doesn’t make you high. As you may know, inside the human body there’s the endocannabinoid system, with receptors spread throughout the brain and body. THC activates the CB1 and CB2 receptors, while CBD does not directly stimulate these receptors. Cannabinoid receptors are involved in a series of processes inside the human body, including the regulation of mood, pain sensation, appetite and memory. These receptors can be activated by endocannabinoids (produced by the human body) as well as by plant cannabinoids (like those found in hemp or cannabis), and they’re grouped in two main categories: CB1 and CB2. CB1 receptors are found mostly in the central nervous system, and in smaller numbers in the liver, kidneys and lungs, while CB2 receptors are part of the immune system and found in the hematopoietic blood cells as well. CB1 play a role in the production and release of neurotransmitters, cannabis products that exert psychoactive effects stimulating these receptors. At the same time, CB1 receptors are involved in the lipogenesis process that takes place inside the liver, and seem to play a role in the maintenance of homeostasis (body’s internal equilibrium). Various studies suggest that CB1 also influence pleasure, concentration and appetite, memory and pain.
HOW MUCH CBD SHOULD YOU TAKE? The dosage amount of CBD per individual and per treatment condition will vary. Taking CBD is somewhat similar to starting a new diet. You can’t expect to lose all the weight after one healthy meal. It takes time. CBD benefits are cumulative, so be patient and consistent to ensure that the potency has time to build up in your system. Allow at least 2 to 3 weeks to see full results. A good rule of thumb is to start with a smaller dose and adjust accordingly. Track your usage and effects, and then use that information to make decisions on your personal dosage that works best for you.
CAN YOU TAKE TOO MUCH CBD OIL? CBD has no known adverse side effects, but an excessive amount of CBD could be less effective therapeutically than a moderate dose. HOW LONG DOES IT TAKE FOR CBD TO TAKE EFFECT? Taking CBD orally takes longer (20-30 mins) to absorb than other methods like vaping which is almost instant. When eating CBD products, some of this hydrophobic (non-water soluble) organic compound tends to diffuse out of the blood and into the fatty tissues. CBD also needs to pass through the gut and liver which also reduce it’s bioavailability in the body. Vaping CBD allows for rapid and more abundant absorption into the blood stream via the lungs, however vaping is not for everyone. Liposomes are also a good option if you are looking for an alternative with better bioavailability than typical oral consumption.
WHAT ARE THE SIDE EFFECTS OF CBD? There are no serious side effects known, however, the following have been reported:
WHAT CAN CBD HELP ME WITH? High concentrations of CBD have been shown to activate the 5-HT1A serotonin receptor, exerting anti-depressant effects. The same receptor is involved in a series of processes from pain perception, appetite, nausea and anxiety to sleep and addiction mechanisms. Talk to a doctor to find out if CBD is right for you.
CAN CBD HELP WITH ANXIETY AND MOOD? Most people have heard of THC or Tetrahydrocannabinol – the one that gets you high – although for many people THC can actually bring on feelings of paranoia and anxiety. However CBD is considered non-psychoactive and an increasing number of studies point towards its anti-inflammatory, neuroprotective and anti-anxiety properties. Cannabis has been used for centuries to treat nerves and anxiety, as well as other mood problems. CBD may help to improve both depression and anxiety, at least in part through its interactions with serotonin receptors in the brain. Research shows that CBD can reduce both mental and physical symptoms of anxiety. So far, most research hasn’t made it beyond the science lab, with very few human trials taking place. However, in the case of CBD and its anxiolytic (anti-anxiety) effects, a number of trials on real, live people have been documented showing that taking CBD does in fact reduce feelings of anxiety. A study of CBD given to people before a public-speaking event indicates that CBD can help reduce stress—this and other research has shown that CBD can be an effective treatment for social anxiety.
CAN CBD HELP WITH SLEEP DISORDERS? CBD has the ability to reduce anxiety, which can be helpful in reducing sleep difficulties and improving sleep quality. CBD may increase overall sleep amounts, and improve insomnia, according to research. CBD has been shown to reduce insomnia in people who suffer from chronic pain. In smaller doses, CBD stimulates alertness and reduces daytime sleepiness, which is important for daytime performance and for the strength and consistency of the sleep-wake cycle.
CAN HEMP OIL BE USED FOR PAIN AND INFLAMMATION? The activation of adenosine receptors by CBD gives the anti-anxiety and anti-inflammatory effects of cannabidiol. Adenosine receptors are also involved in the release of dopamine and glutamate, two neurotransmitters that play major roles inside the body. Dopamine is involved in cognition, motor control, motivation and reward mechanisms, while glutamate is one of the major mediators of excitatory signals, being involved in memory, learning and cognition. Cannabidiol (CBD) oil is used by some people with chronic pain from certain illnesses and medical conditions. Researchers think that CBD interacts with receptors in your brain and immune system. Receptors are tiny proteins attached to your cells that receive chemical signals from different stimuli and help your cells respond. This creates anti-inflammatory and painkilling effects that help with pain management. This means that CBD oil may benefit people with chronic pain, such as chronic back pain.
CAN CBD HELP WITH ALCOHOLISM AND ADDICTION? When CBD is taken into the system, CB1 receptors receive a large amount of CBD, resulting in a feeling of satisfaction or “having been rewarded”. CBD receptors are located in the brain, abdomen and reproductive area. The brain is most affected by alcohol, so it is very important to take a sufficient amount of CBD to combat the alcoholism. When you take CBD it will stop the craving for alcohol and suppress the negative effects of alcoholism. Therefore, when an alcohol-dependent person attempts to reduce or eliminate their alcohol consumption, treatments to increase the signals of cannabinoid receptors in the brain may prove to be useful, my statement to be motivated as follows:
Cannabinoids are likely to act as neuroprotective (nerve protecting) agents having the potential to limit hyper-excitability and therefore preventing brain cell damage. Therefore, Cannabinoid therapy may actively avert the brain damage that would otherwise have been caused by withdrawal;
Using CBD in conjunction with eliminating alcohol may be useful in treating alcohol dependence and alcohol withdrawal by helping to prevent alcohol cravings. CBD treatment for alcohol is still a new concept, but it does have a lot of potential.
WILL CBD CAUSE A FAILED DRUG TEST?
No. CBD is considered to be undetectable in saliva or urine tests. However, consuming unusually large dosages of CBD, such as 1,000 to 2,000 milligrams per day, could theoretically trigger a positive for THC on a urine test through trace amounts found with CBD — but that would be a false positive.